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  • Chromosome Translocation
    Chromosome Translocation

    This volume discusses various aspects of mechanisms and methodologies of chromosome translocations, ranging from a historical and clinical overview of chromosome translocations to the rapid development of the next-generation sequencing technologies, which has dramatically increased our understanding of the spectrum of chromosome translocations in human diseases. The book also introduces the mechanistic studies on chromosome deletions and their implications in cancer, and discusses the mechanisms of regulating chromothripsis, a unique complex type of chromosome translocation. It is a valuable resource for students and researchers alike, providing insights into chromosome translocations and, potentially, other genomic aberrations involved in understanding and curing human diseases.

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  • The Calcutta Chromosome
    The Calcutta Chromosome

    In this extraordinary novel, Amitav Ghosh navigates through time and genres to present a unique tale.Beginning at an unspecified time in the future and ranging back to the late nineteenth century, the reader follows the adventures of the enigmatic L.Murugan. An authority on the Nobel Prize-winning scientist Sir Ronald Ross, who solved the malaria puzzle in Calcutta in 1898, Murugan is in search of the elusive 'Calcutta Chromosome'. With its astonishing range of characters, advanced computer science, religious cults and wonderful portraits of Victorian and contemporary India, The Calcutta Chromosome expands the scope of the novel as we know it, as Amitav Ghosh takes on the avatar of a science thriller writer.

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  • Human Chromosome Atlas : Introduction to Diagnostics of Structural Aberrations
    Human Chromosome Atlas : Introduction to Diagnostics of Structural Aberrations

    Now in its second edition, this atlas serves as an easy-to-use diagnostic guide for the analysis of the human karyotype. Split in four parts, it starts with a comprehensive introduction covering the molecular cytogenetic basics, the role of ethic committees and international quality control in the field of diagnostics.The main parts II and III show the spectrum of different types of chromosomal abnormalities by a combination of karyogram and ideogram.They compare the significance of different banding techniques, give the karyotype formula and describe morphological peculiarities of each case presented.The final part provides a detailed description of non-coding DNA variants and focuses on potential problems in the detection of aberrations.It also mentions necessary additional investigations and peculiarities to be considered when counselling carriers of a chromosomal aberration or their relatives. Given its comprehensive scope and practical approach, this atlas is an indispensable resource for researchers, clinicians and practitioners working in the field of cytogenetics and clinical genetics.

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  • The Talent Management of Indie Authorship : From American Independent Cinema and Short Films to Pay-Tv and Streaming
    The Talent Management of Indie Authorship : From American Independent Cinema and Short Films to Pay-Tv and Streaming

    This book explores the role that talent intermediaries, including talent agents, talent managers and producers, play in packaging, marketing and selling screen media products, services and brands by constructing and positioning their clients and collaborators as indie-auteurs.Exploring several case-studies across a range of screen media during an era of media convergence, including American indie cinema, high-end television, music video, advertising and branded content, the book explores the strategies that talent intermediaries adopt and the industrial, cultural and social connotations and hierarchies that indie-auteurism as a promotional discourse and tool carries and reinforces.As a result, the book stakes out new ground that complicates popular ideas of indie-auteurs as highly autonomous and innovative filmmakers by exploring how this authorial discourse migrates between media and is constructed and reconfigured in relation to changing industrial and cultural contexts.

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  • How big is a chromosome?

    A chromosome is a long, continuous strand of DNA that contains numerous genes. The size of a chromosome can vary widely between different species, but in humans, the largest chromosome, chromosome 1, is about 248 million base pairs long, while the smallest, chromosome 21, is about 46 million base pairs long. In physical terms, if we were to stretch out the DNA in a single human cell, the total length of all the chromosomes combined would be about 6 feet long.

  • What exactly is a chromosome?

    A chromosome is a thread-like structure made of DNA and proteins found in the nucleus of a cell. It carries genetic information in the form of genes, which determine an organism's traits and characteristics. Humans typically have 23 pairs of chromosomes, with one set inherited from each parent. During cell division, chromosomes condense and become visible under a microscope, allowing for the accurate distribution of genetic material to daughter cells.

  • What is a chromosome anomaly?

    A chromosome anomaly, also known as a chromosomal abnormality, is a structural or numerical change in the DNA of a chromosome. This can occur due to errors in cell division, exposure to certain environmental factors, or genetic mutations. Chromosome anomalies can result in a wide range of genetic disorders and health conditions, including Down syndrome, Turner syndrome, and Klinefelter syndrome. These anomalies can impact an individual's physical and intellectual development, and may require medical intervention and support.

  • What is the crossing-over process between the X chromosome and the Y chromosome?

    The crossing-over process between the X and Y chromosomes occurs during meiosis, the process of cell division that produces gametes (sperm and eggs). During meiosis, homologous chromosomes (such as the X and Y chromosomes) exchange genetic material through a process called crossing-over. This results in the exchange of segments of DNA between the X and Y chromosomes, leading to genetic variation in the offspring. The crossing-over process is important for genetic diversity and ensures that each gamete produced is genetically unique.

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  • FilmQuake : The Most Disruptive Films in Cinema
    FilmQuake : The Most Disruptive Films in Cinema

    Discover films that dared to be different, risked reputations and put careers in jeopardy.This is what happens when filmmakers take tradition and rip it up. FilmQuake introduces 50 movies that shook the cinematic world, telling the fascinating stories behind their creation, reception and legacy. From unbelievable developments in technology (Citizen Kane, 1941) to feminist triumphs (Wanda, 1970); films that kickstarted New Queer Cinema (Paris is Burning, 1990) to others that challenged lawmakers (A Short Film About Killing, 1988) – FilmQuake presents the movies that questioned boundaries, challenged the status quo and made shockwaves we are still feeling today. From film's first innovators, people like the Lumière brothers, whose short film of a train arriving was reported to have terrified audiences in 19th century Paris, through iconoclasts like Sergei Eisenstein and Luis Buñuel, to titans of 20th century cinema like Alfred Hitchcock and Jean-Luc Godard, discover the stories behind the films which incontrovertably changed the course of cinema forever. Into the modern day, this book examines how filmmakers have addressed themes of prejudice and inequality, from the Black Lives Matter movement and Jordan Peele's unmissable Get Out to Bong Joon-ho's cutting study of the lives of the wealthy in Parasite, as well as innovative new cinematic techniques emerging in films like 28 Days Later and Blair Witch Project. In telling the history of cinema through the works that were truly disruptive, and explaining the context in which each was created, FilmQuake demonstrates the heart of modern film, which is to constantly question boundaries and challenge expectation. This book is from the Culture Quake series, which looks into iconic moments of culture which truly created paradigm shifts in their respective fields. Also available is ArtQuake, which tells the stories of 50 pivotal works that challenged consensus and broke daring new ground in the world of art, inspiring shock and scandal as they did so, but ultimately cementing themselves as truly great works of modern art.

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  • The Cinema of Yorgos Lanthimos : Films, Form, Philosophy
    The Cinema of Yorgos Lanthimos : Films, Form, Philosophy

    From the critical and commercial fanfare his films generate, it is largely understood that Yorgos Lanthimos is one of the more interesting filmmakers to have emerged out of the new century.A markedly transnational filmmaker, between Dogtooth and The Favourite Lanthimos has managed to traverse the gap between the art-house and mainstream while not once sacrificing his unique style and worldview.His films, while often difficult, showcase his talents as a filmmaker, collaborator, and commentator on the human condition.Accompanied by a trademark acerbic wit, Lanthimos's films take aim at humanity's more contemptible and absurd designs as he explores a thematic preoccupation with, among other things, power, trauma, isolation, sex, and violence. This edited collection covers everything from an early career that was marked by experimentation with a range of different media to international festival hits including Dogtooth, The Lobster, The Killing of a Sacred Deer, and the Academy Award-winning "historical" epic The Favourite, Lanthimos's most successful feature to date.All his work demonstrates a fascinating contravention of aesthetic, thematic, and generic boundaries that forms the basis of some of the analyses to be found here.Featuring a roster of talented scholars, both new and established, The Cinema of Yorgos Lanthimos: Films, Form, Philosophy provides a timely compendium of critical approaches to one of the most distinct voices in contemporary film.

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  • Films That Spill : Beyond the Cinema of Transgression
    Films That Spill : Beyond the Cinema of Transgression

    Films That Spill is a comprehensive study of the Cinema of Transgression, a hitherto under-examined moment in US underground film culture.Reconsidering the concept of transgressive cinema not only as a description of the intentionally provocative content of the films, but rather as a feature of a cross-disciplinary practice, the book explores how filmmaking in the context of the vibrant and intermingling art, music, performance, and film scenes in 1980s Lower Manhattan spilled over the boundaries of artistic disciplines, media formats, and content concepts.This study not only provides a microhistory of these scenes and insight into their afterlife in archives and exhibitions.It also represents an innovative contribution to debates within film, media, and visual culture about the methodological and historiographical challenges posed by the expansion of film beyond the discursive boundaries of cinema.

    Price: 23.99 £ | Shipping*: 3.99 £
  • Films That Spill : Beyond the Cinema of Transgression
    Films That Spill : Beyond the Cinema of Transgression

    Films That Spill is a comprehensive study of the Cinema of Transgression, a hitherto under-examined moment in US underground film culture.Reconsidering the concept of transgressive cinema not only as a description of the intentionally provocative content of the films, but rather as a feature of a cross-disciplinary practice, the book explores how filmmaking in the context of the vibrant and intermingling art, music, performance, and film scenes in 1980s Lower Manhattan spilled over the boundaries of artistic disciplines, media formats, and content concepts.This study not only provides a microhistory of these scenes and insight into their afterlife in archives and exhibitions.It also represents an innovative contribution to debates within film, media, and visual culture about the methodological and historiographical challenges posed by the expansion of film beyond the discursive boundaries of cinema.

    Price: 99.00 £ | Shipping*: 0.00 £
  • What is the difference between a 1-chromatid chromosome and a 2-chromatid chromosome?

    A 1-chromatid chromosome, also known as a single chromatid chromosome, consists of a single DNA molecule and is present during the early stages of the cell cycle. On the other hand, a 2-chromatid chromosome, also known as a double chromatid chromosome, consists of two identical DNA molecules, called sister chromatids, that are joined together at the centromere. 2-chromatid chromosomes are formed during the S phase of the cell cycle when DNA is replicated.

  • Why can one survive with an X chromosome, but not with just a Y chromosome?

    One can survive with just an X chromosome because it contains a large number of essential genes that are necessary for normal development and function of the body. However, the Y chromosome is much smaller and contains fewer genes, most of which are related to male reproductive development. Without the essential genes found on the X chromosome, an individual would not be able to survive. Therefore, having only a Y chromosome is not sufficient for survival.

  • What is a chromosome made of?

    A chromosome is made of DNA, which is a long molecule that carries genetic information. DNA is tightly coiled and packaged around proteins called histones to form a structure known as chromatin. Chromosomes also contain other proteins that help regulate gene expression and control cell division. Each chromosome consists of a single DNA molecule that contains many genes, which are the instructions for making proteins that determine an organism's traits.

  • Which chromosome set is being read?

    The chromosome set being read is the diploid set, which includes two sets of chromosomes, one from each parent. This set of chromosomes contains the complete genetic information of an individual and is used by the cell to carry out various functions such as protein synthesis and cell division. The diploid set is essential for the proper development and functioning of an organism.

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